UMUC: Bioinformatics Studies
The Master of Science program in biotechnology serves a number of careers at the entry-, mid-, or high-level positions, depending on the prior level of experience of the candidate.
A specialization in Bioformatics covers a broad range of subjects (for example, biostatistics, databases and data structures, algorithms, gene expression analysis, and PERL) at the interface of molecular biology and computational science. [read more]

A guide to bioinformatics resources on the internet
The following list contains link to various bioinformatics related resources available on the internet. This list is by no means exhaustive, but does cover a large bulk of the bioinformatics material and subject matters. [read more]

Online Lectures on Bioinformatics
In the current context we can only give an extremely brief introduction to the basic notions of molecular biology. An overview can be found in any modern textbook on biology, biochemistry or molecular biology [read more]

Centre for Molecular and Biomolecular Informatics
The C MB I offers a number of Courses on Bioinformatics and Cheminformatics topics, which are described elsewhere, as well as a number of Interactive Web Tutorials.
These online tutorials are available for anyone to browse, but we know from years of experience teaching computational biology and chemistry courses at the CMBI that doing carefully designed exercises with an experienced instructor close at hand is the best way to learn. [read more]

Analysis Tools for Computational Biology

BioINFO Project is a free, open source platform for students, educators, and researchers.
[Click Here] to try our genome analysis tools.

What is bioinformatics?

Bioinformatics is the application of computer technology to the management of biological information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied to scientific research, gene-based drug discovery and development. The need for bioinformatics capabilities has been precipitated by the explosion of publicly available genomic information resulting from the Human Genome Project. The goal of this project – determination of the sequence of the entire human genome (approximately three billion base pairs) was reached in 2003. The science of bioinformatics, which is the melding of molecular biology with computer science, is essential to the use of genomic information in understanding biological evolution, human diseases, and in the identification of new molecular targets for drug discovery. In recognition of this, many universities, government institutions and pharmaceutical firms have formed bioinformatics groups, consisting of computational biologists and bioinformatics computer scientists. Such groups will be key to unraveling the mass of information generated by large scale sequencing efforts underway in laboratories around the world.

Why is bioinformatics important?

The greatest challenge facing the molecular biology community today is to make sense of the wealth of data that has been produced by the genome sequencing projects. Traditionally, molecular biology research was carried out entirely at the experimental laboratory bench but the huge increase in the scale of data being produced in this genomic era has seen a need to incorporate computers into this research process.

Sequence generation, and its subsequent storage, interpretation and analysis are entirely computer dependent tasks. However, the molecular biology of an organism is a very complex issue with research being carried out at different levels including the genome, proteome, transcriptome and metabalome levels. Following on from the explosion in volume of genomic data, similar increase in data have been observed in the fields of proteomics, transcriptomics and metabalomics.

The first challenge facing the bioinformatics community today is the intelligent and efficient storage of this mass of data. It is then their responsibility to provide easy and reliable access to this data. The data itself is meaningless before analysis and the sheer volume present makes it impossible for even a trained biologist to begin to interpret it manually. Therefore, incisive computer tools must be developed to allow the extraction of meaningful biological information.

There are three central biological processes around which bioinformatics tools must be developed:

  • DNA sequence determines protein sequence
  • Protein sequence determines protein structure
  • Protein structure determines protein function

The integration of information learned about these key biological processes should allow us to achieve the long term goal of the complete understanding of the biology of organisms.

How is BioINFO Project involved with bioinformatics?

BioINFO Project, a division of Pangaea Biosciences, was created as a free, open source platform for students, educators, and researchers. At Pangaea Biosciences, we value the importance of scientific excellence. We strongly believe the field(s) of biotechnology:bioinformatics present a number of vital opportunities. By employing the latest scientific applications toward medicine and biology, Pangaea Biosciences seeks to help improve techniques for medical treatments & diagnostics, personal & homeland security, environmental monitoring & ecosystem restoration, water & food safety, evolutionary studies and much more. We are dedicated to upholding our commitment to serving you, our community, and the integrity of our profession.

The main initiative of BioINFO Project is to provide a wide array of integrative tools & applications to better equip private corporations and academic institutions toward scientific advancement.

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